Melatonin-loaded self-healing hydrogel targets mitochondrial energy metabolism and promotes annulus fibrosus regeneration

Intervertebral disc (IVD) herniation is a major cause of chronic low back pain and disability. The current nucleus pulposus (NP) discectomy effectively relieves pain symptoms, but the annulus fibrosus (AF) defects are left unrepaired. Tissue engineering approaches show promise in treating AF injury...

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Main Authors: Xiayu Hu, Xin Tian, Chunju Yang, Feng Ling, Hao Liu, Xuesong Zhu, Ming Pei, Huilin Yang, Tao Liu, Yong Xu, Fan He
格式: 文件
语言:English
出版: Elsevier 2023-12-01
丛编:Materials Today Bio
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在线阅读:http://www.sciencedirect.com/science/article/pii/S2590006423002715