Rationale and design of a multi-center, open-label, randomised clinical trial comparing HIV incidence and contraceptive benefits in women using three commonly-used contraceptive methods (the ECHO study) [version 1; referees: 2 approved]

Background: In vitro, animal, biological and observational clinical studies suggest that some hormonal methods, particularly depot medroxyprogesterone acetate – DMPA, may increase women’s risk of HIV acquisition. DMPA is the most common contraceptive used in many countries worst affected by the HIV...

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Bibliographic Details
Main Authors: G. Justus Hofmeyr, Charles S. Morrison, Jared M. Baeten, Tsungai Chipato, Deborah Donnell, Peter Gichangi, Nelly Mugo, Kavita Nanda, Helen Rees, Petrus Steyn, Douglas Taylor, ECHO Trial Team
Format: Article
Language:English
Published: F1000 Research Ltd 2017-12-01
Series:Gates Open Research
Online Access:https://gatesopenresearch.org/articles/1-17/v1