Correlation between NK function and response to trastuzumab in metastatic breast cancer patients

<p>Abstract</p> <p>Background</p> <p>Trastuzumab is a monoclonal antibody selectively directed against Her2 and approved for the treatment of Her2 overexpressing breast cancer patients. Its proposed mechanisms of action include mediation of antibody-dependent cellular c...

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Bibliographic Details
Main Authors: Spadi Rosella, Polimeni Maria, Mistrangelo Marinella, Brusa Davide, Evangelista Andrea, Signorino Elena, Beano Alessandra, Donadio Michela, Ciuffreda Libero, Matera Lina
Format: Article
Language:English
Published: BMC 2008-05-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/6/1/25