A Linear Fragment of Unacylated Ghrelin (UAG6−13) Protects Against Myocardial Ischemia/Reperfusion Injury in Mice in a Growth Hormone Secretagogue Receptor-Independent Manner

A Linear Fragment of Unacylated Ghrelin (UAG6−13) Protects Against Myocardial Ischemia/Reperfusion Injury in Mice in a Growth Hormone Secretagogue Receptor-Independent Manner

Unacylated ghrelin (UAG), the most abundant form of ghrelin in circulation, has been shown to exert cardioprotective effect in experimental cardiopathies. The present study aimed to investigate the cardioprotective effect of a linear bioactive fragment of UAG against myocardial ischemia-induced inju...

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Bibliographic Details
Main Authors: David N. Huynh, Hanan Elimam, Valérie L. Bessi, Liliane Ménard, Yan Burelle, Riccarda Granata, André C. Carpentier, Huy Ong, Sylvie Marleau
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Endocrinology
Subjects:
cardiac ischemia/reperfusion
unacylated ghrelin analogs
hemodynamics
growth hormone secretagogue receptor
tumor necrosis factor-α
interleukin-6
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00798/full

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https://www.frontiersin.org/article/10.3389/fendo.2018.00798/full

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