Protocol for chemogenetic activation of basal ganglia D1-MSNs and behavioral assessments in a primate Parkinson’s disease model
Summary: A circuit-based gene therapy strategy for Parkinson’s disease (PD) has been shown to significantly reverse core symptoms in both murine and primate PD models. Here, we present a comprehensive workflow to specifically manipulate dopamine receptor D1-expressing medium spiny neurons by retrogr...
প্রধান লেখক: | , , , , , , , , , , , , , , |
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বিন্যাস: | প্রবন্ধ |
ভাষা: | English |
প্রকাশিত: |
Elsevier
2024-12-01
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মালা: | STAR Protocols |
বিষয়গুলি: | |
অনলাইন ব্যবহার করুন: | http://www.sciencedirect.com/science/article/pii/S266616672400635X |