Cytokinetic abscission requires actin-dependent microtubule severing

Abstract Cell division is completed by the abscission of the intercellular bridge connecting the daughter cells. Abscission requires the polymerization of an ESCRT-III cone close to the midbody to both recruit the microtubule severing enzyme spastin and scission the plasma membrane. Here, we found t...

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Bibliographic Details
Main Authors: Tamara Advedissian, Stéphane Frémont, Arnaud Echard
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46062-9