Histone demethylase KDM5A regulates the functions of human periodontal ligament stem cells during periodontitis via the miR-495-3p/HOXC8 axis

Histone demethylase KDM5A regulates the functions of human periodontal ligament stem cells during periodontitis via the miR-495-3p/HOXC8 axis

Introduction: Periodontitis is the sixth most common human disease and epigenetic regulation is identified to affect the functions of stem cells. This research aims to analyze the role of histone demethylase Lysine-specific demethylase 5A (KDM5A) in human periodontal ligament stem cells (hPDLSCs) wi...

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Bibliographic Details
Main Authors: Fang Niu, Jing Xu, Yujuan Yan
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Regenerative Therapy
Subjects:
Periodontitis
hPDLSCs
Histone demethylase
KDM5A
miR-495-3p
Stem cell function
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320421000997

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http://www.sciencedirect.com/science/article/pii/S2352320421000997

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