Synthesis, Characterization, ADME Study and Anti-proliferative evaluation against MCF-7 breast cancer cell line of new analog of a 4-aminophenyl quinazolinone derivative

New series of 4-aminophenyl quinazolinone attached to an aromatic aldehyde moiety has been designed. Compound (ZA) was synthesized by a reaction of benzene-1,4-diamine with 2-aminobenzoic acid. The reaction between (ZA) intermediate and different substituted aromatic aldehydes (R1- R6) is consid...

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Bibliographic Details
Main Authors: Zainab A. Jabbar, Monther F. Mahdi, Basma M.Abd Razik
Format: Article
Language:English
Published: College of Pharmacy / Mustansiriyah University 2023-10-01
Series:Al-Mustansiriyah Journal of Pharmaceutical Sciences
Subjects:
Online Access:https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/1096