Keratin 19 binds and regulates cytoplasmic HNRNPK mRNA targets in triple-negative breast cancer

Keratin 19 binds and regulates cytoplasmic HNRNPK mRNA targets in triple-negative breast cancer

Abstract Background Heterogeneous nuclear ribonucleoprotein K (HNRNPK) regulates pre-mRNA processing and long non-coding RNA localization in the nucleus. It was previously shown that shuttling of HNRNPK to the cytoplasm promotes cell proliferation and cancer metastasis. However, the mechanism of HNR...

Full description

Bibliographic Details
Main Authors: Arwa Fallatah, Dimitrios G. Anastasakis, Amirhossein Manzourolajdad, Pooja Sharma, Xiantao Wang, Alexis Jacob, Sarah Alsharif, Ahmed Elgerbi, Pierre A. Coulombe, Markus Hafner, Byung Min Chung
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Molecular and Cell Biology
Subjects:
Keratin 19
HNRNPK
PAR-CLIP
Gene expression
Breast Cancer
p53
Online Access:https://doi.org/10.1186/s12860-023-00488-z

Internet

https://doi.org/10.1186/s12860-023-00488-z

Similar Items