Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression
Background Despite their revolutionary success in cancer treatment over the last decades, immunotherapies encounter limitations in certain tumor types and patients. The efficacy of immunotherapies depends on tumor antigen-specific CD8 T-cell viability and functionality within the immunosuppressive t...
Autors principals: | , , , , , , |
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Format: | Article |
Idioma: | English |
Publicat: |
BMJ Publishing Group
2023-05-01
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Col·lecció: | Journal for ImmunoTherapy of Cancer |
Accés en línia: | https://jitc.bmj.com/content/11/5/e005719.full |