The multifaceted roles of the matrikine Pro-Gly-Pro in pulmonary health and disease

Matrikines are bioactive fragments of the extracellular matrix (ECM) that are fundamental in regulating a diverse array of physiological processes. The tripeptide Proline-Glycine-Proline (PGP) is a collagen-derived matrikine that has classically been described as a neutrophil chemoattractant. In thi...

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Bibliographic Details
Main Authors: Dhiren F. Patel, Robert J. Snelgrove
Format: Article
Language:English
Published: European Respiratory Society 2018-06-01
Series:European Respiratory Review
Online Access:http://err.ersjournals.com/content/27/148/180017.full