Trypanosoma cruzi infection is a potent risk factor for non-alcoholic steatohepatitis enhancing local and systemic inflammation associated with strong oxidative stress and metabolic disorders.

BACKGROUND:The immune mechanisms underlying experimental non-alcoholic steatohepatitis (NASH), and more interestingly, the effect of T. cruzi chronic infection on the pathogenesis of this metabolic disorder are not completely understood. METHODOLOGY/PRINCIPAL FINDINGS:We evaluated immunological para...

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Bibliographic Details
Main Authors: Luisina I Onofrio, Alfredo R Arocena, Augusto F Paroli, María E Cabalén, Marta C Andrada, Roxana C Cano, Susana Gea
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4323252?pdf=render