53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication

53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication

Summary: RNA-binding proteins (RBPs) are found at replication forks, but their direct interaction with DNA-embedded RNA species remains unexplored. Here, we report that p53-binding protein 1 (53BP1), involved in the DNA damage and replication stress response, is an RBP that directly interacts with O...

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Bibliographic Details
Main Authors: Melissa Leriche, Clara Bonnet, Jagannath Jana, Gita Chhetri, Sabrina Mennour, Sylvain Martineau, Vincent Pennaneach, Didier Busso, Xavier Veaute, Pascale Bertrand, Sarah Lambert, Kumar Somyajit, Patricia Uguen, Stéphan Vagner
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Cell Reports
Subjects:
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723014249

Internet

http://www.sciencedirect.com/science/article/pii/S2211124723014249

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