Sperm deoxyribonucleic acid fragmentation index at the time of intracytoplasmic sperm injection and standard in vitro fertilization is correlated with lower fertilization but not with blastocyst genetic diagnosis

Sperm deoxyribonucleic acid fragmentation index at the time of intracytoplasmic sperm injection and standard in vitro fertilization is correlated with lower fertilization but not with blastocyst genetic diagnosis

Objective: To determine the effects of sperm deoxyribonucleic acid (DNA) fragmentation at the time of fertilization on in vitro fertilization (IVF) outcomes and genetic diagnosis using next generation sequencing. Design: Prospective double-blinded study. Setting: Private Clinic. Patients: Couples (n...

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Bibliographic Details
Main Authors: Alicia L. Broussard, Ph.D., H.C.L.D., Benjamin Leader, M.D., Edna Tirado, Ph.D., Helena Russell, M.S., Hind Beydoun, Ph.D., Robert Colver, M.D., Laura Reuter, M.D., Bradford Bopp, M.D., Matthew Will, M.D., Erica Anspach Will, M.D., Glen Adaniya, Ph.D., H.C.L.D.
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:F&S Reports
Subjects:
Sperm DNA fragmentation
Preimplantation genetic testing
fertilization
IVF outcomes
DFI
Online Access:http://www.sciencedirect.com/science/article/pii/S2666334123000466

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http://www.sciencedirect.com/science/article/pii/S2666334123000466

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