HCCS1-armed, quadruple-regulated oncolytic adenovirus specific for liver cancer as a cancer targeting gene-viro-therapy strategy

HCCS1-armed, quadruple-regulated oncolytic adenovirus specific for liver cancer as a cancer targeting gene-viro-therapy strategy

<p>Abstract</p> <p>Background</p> <p>In previously published studies, oncolytic adenovirus-mediated gene therapy has produced good results in targeting cancer cells. However, safety and efficacy, the two most important aspects in cancer therapy, remain serious challenge...

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Bibliographic Details
Main Authors: Xu Hai-Neng, Huang Wei-Dan, Cai Ying, Ding Miao, Gu Jin-Fa, Wei Na, Sun Lan-Ying, Cao Xin, Li Hua-Guang, Zhang Kang-Jian, Liu Xin-Ran, Liu Xin-Yuan
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Molecular Cancer
Subjects:
liver cancer
quadruple regulated adenovirus
HCCS1
mitochondrial apoptosis pathway
Online Access:http://www.molecular-cancer.com/content/10/1/133

Internet

http://www.molecular-cancer.com/content/10/1/133

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