Platelet-rich concentrate in serum-free medium enhances cartilage-specific extracellular matrix synthesis and reduces chondrocyte hypertrophy of human mesenchymal stromal cells encapsulated in alginate

Platelet-rich concentrate in serum-free medium enhances cartilage-specific extracellular matrix synthesis and reduces chondrocyte hypertrophy of human mesenchymal stromal cells encapsulated in alginate

Platelet-rich concentrate (PRC), used in conjunction with other chondroinductive growth factors, have been shown to induce chondrogenesis of human mesenchymal stromal cells (hMSC) in pellet culture. However, pellet culture systems promote cell hypertrophy and the presence of other chondroinductive g...

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Bibliographic Details
Main Authors: Shani Samuel, Raja Elina Ahmad, Thamil Selvee Ramasamy, Puvanan Karunanithi, Sangeetha Vasudevaraj Naveen, Tunku Kamarul
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Platelets
Subjects:
blood
cartilage repair
chondrogenesis
extra-cellular matrix
regenerative medicine
stem cells
tissue engineering
Online Access:http://dx.doi.org/10.1080/09537104.2017.1371287

Internet

http://dx.doi.org/10.1080/09537104.2017.1371287

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