Improved Dissolution and Pharmacokinetics of Abiraterone through KinetiSol<sup>®</sup> Enabled Amorphous Solid Dispersions

Abiraterone is a poorly water-soluble drug. It has a high melting point and limited solubility in organic solvents, making it difficult to formulate as an amorphous solid dispersion (ASD) with conventional technologies. KinetiSol<sup>®</sup> is a high-energy, fusion-based, solvent-free t...

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Bibliographic Details
Main Authors: Urvi Gala, Dave Miller, Robert O. Williams
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/12/4/357