Improved Dissolution and Pharmacokinetics of Abiraterone through KinetiSol<sup>®</sup> Enabled Amorphous Solid Dispersions

Improved Dissolution and Pharmacokinetics of Abiraterone through KinetiSol<sup>®</sup> Enabled Amorphous Solid Dispersions

Abiraterone is a poorly water-soluble drug. It has a high melting point and limited solubility in organic solvents, making it difficult to formulate as an amorphous solid dispersion (ASD) with conventional technologies. KinetiSol<sup>®</sup> is a high-energy, fusion-based, solvent-free t...

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Bibliographic Details
Main Authors:	Urvi Gala, Dave Miller, Robert O. Williams
Format:	Article
Language:	English
Published:	MDPI AG 2020-04-01
Series:	Pharmaceutics
Subjects:	abiraterone dissolution pharmacokinetics amorphous solid dispersions KinetiSol<sup>®</sup> technology
Online Access:	https://www.mdpi.com/1999-4923/12/4/357

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