Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells.

Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells.

Fragile X syndrome (FXS), the most common form of inherited mental retardation, is caused by the loss of functional fragile X mental retardation protein (FMRP). FMRP is an RNA-binding protein that can regulate the translation of specific mRNAs. Adult neurogenesis, a process considered important for...

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Bibliographic Details
Main Authors: Yuping Luo, Ge Shan, Weixiang Guo, Richard D Smrt, Eric B Johnson, Xuekun Li, Rebecca L Pfeiffer, Keith E Szulwach, Ranhui Duan, Basam Z Barkho, Wendi Li, Changmei Liu, Peng Jin, Xinyu Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2851565?pdf=render

Internet

http://europepmc.org/articles/PMC2851565?pdf=render

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