Diffusion basis spectrum imaging detects subclinical traumatic optic neuropathy in a closed-head impact mouse model of traumatic brain injury

Diffusion basis spectrum imaging detects subclinical traumatic optic neuropathy in a closed-head impact mouse model of traumatic brain injury

IntroductionTraumatic optic neuropathy (TON) is the optic nerve injury secondary to brain trauma leading to visual impairment and vision loss. Current clinical visual function assessments often fail to detect TON due to slow disease progression and clinically silent lesions resulting in potentially...

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Bibliographic Details
Main Authors: Hsin-Chieh Yang, Raj Swaroop Lavadi, Andrew D. Sauerbeck, Michael Wallendorf, Terrance T. Kummer, Sheng-Kwei Song, Tsen-Hsuan Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Neurology
Subjects:
traumatic optic neuropathy
traumatic brain injury
diffusion MRI
diffusion basis spectrum imaging
axonal loss
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1269817/full

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https://www.frontiersin.org/articles/10.3389/fneur.2023.1269817/full

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