LncRNA-84277 is involved in chronic pain-related depressive behaviors through miR-128-3p/SIRT1 axis in central amygdala

LncRNA-84277 is involved in chronic pain-related depressive behaviors through miR-128-3p/SIRT1 axis in central amygdala

Long-term chronic pain can lead to depression. However, the mechanism underlying chronic pain-related depression remains unclear. Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD+)-dependent histone deacetylase (HDAC). Our previous studies have demonstrated that SIRT1 in the central nuc...

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Bibliographic Details
Main Authors: Xiaowei Jiao, Ruiyao Wang, Xiaobao Ding, Binbin Yan, Yuwen Lin, Qiang Liu, Yuqing Wu, Chenghua Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
pain
depression
SIRT1
lncRNA-84277
miR-128-3p
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.920216/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.920216/full

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