Hematopoietic stem and progenitor cells use podosomes to transcellularly cross the bone marrow endothelium

Bone marrow endothelium plays an important role in the homing of hematopoietic stem and progenitor cells upon transplantation, but surprisingly little is known on how the bone marrow endothelial cells regulate local permeability and hematopoietic stem and progenitor cells transmigration. We show th...

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Bibliographic Details
Main Authors: Timo Rademakers, Marieke Goedhart, Mark Hoogenboezem, Alexander García Ponce, Jos van Rijssel, Maryna Samus, Michael Schnoor, Stefan Butz, Stephan Huveneers, Dietmar Vestweber, Martijn A. Nolte, Carlijn Voermans, Jaap D. van Buul
Format: Article
Language:English
Published: Ferrata Storti Foundation 2020-01-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/9624