Tumor-derived KLK8 predicts inferior survival and promotes an immune-suppressive tumor microenvironment in lung squamous cell carcinoma

Tumor-derived KLK8 predicts inferior survival and promotes an immune-suppressive tumor microenvironment in lung squamous cell carcinoma

Abstract Lung squamous cell carcinoma (LUSC) is the second most common lung cancer worldwide, leading to millions of deaths annually. Although immunotherapy has expanded the therapeutic choices for LUSC and achieved considerable efficacy in a subset of patients, many patients could not benefit, and...

Full description

Bibliographic Details
Main Authors: He Tian, Ran Wei, Chu Xiao, Tao Fan, Yun Che, Tiejun Liu, Bo Zheng, Chunxiang Li, Jie He
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Pulmonary Medicine
Subjects:
KLK8
Squamous cell lung carcinoma (LUSC)
Prognosis
Tumor immune microenvironment (TIME)
Biomarker
Online Access:https://doi.org/10.1186/s12890-023-02770-4

Internet

https://doi.org/10.1186/s12890-023-02770-4

Similar Items