Selective synthesis, structural studies and antitumor evaluation of some novel unsymmetrical 1-hetaryl-4-(2-chloroquinolin-3-yl)azines

A series of novel unsymmetrical 1-hetaryl-4-(2-chloroquinolin-3-yl) azines 4–9 was selectively synthesized in a three-step procedure starting from acetanilide (1). The molecular structures of 4–9 were established by elemental analyses, spectral data, hybrid density functional theory (DFT) and time-d...

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Bibliographic Details
Main Authors: Samir Bondock, Hanaa Gieman, Ahmed El-Shafei
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Journal of Saudi Chemical Society
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610315000101