High fat diet significantly changed the global gene expression profile involved in hepatic drug metabolism and pharmacokinetic system in mice

High fat diet significantly changed the global gene expression profile involved in hepatic drug metabolism and pharmacokinetic system in mice

Abstract Background High fat diet impact transcription of hepatic genes responsible for drug metabolism and pharmacokinetics. Until now, researches just focused on a couple specific genes without a global profile showing. Age-dependent manner was also not noted well. This study aims to investigate t...

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Bibliographic Details
Main Authors: Yuqi He, Tao Yang, Yimei Du, Lin Qin, Feifei Ma, Zunping Wu, Hua Ling, Li Yang, Zhengtao Wang, Qingdi Zhou, Guangbo Ge, Yanliu Lu
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Nutrition & Metabolism
Subjects:
High fat diet
Drug metabolism and pharmacokinetic
RNA-Seq
Transcriptome
Online Access:http://link.springer.com/article/10.1186/s12986-020-00456-w

Internet

http://link.springer.com/article/10.1186/s12986-020-00456-w

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