The generation and validation of two NKX2-5 fluorescent reporter human embryonic stem cell lines: UMANe002-A-1 and UMANe002-A-2

The transcription factor NKX2-5 is a highly conserved master regulator of heart development which is widely expressed in cardiac progenitors and cardiomyocytes. Fluorescent reporters of NKX2-5 that minimally perturb normal protein expression can enable the identification, quantification and isolatio...

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Bibliographic Details
Main Authors: M. Douglas, C. O'Loughlin, A.T. Lynch, R. Prialgauskaite, A.D. Adamson, K.M. Dibb, S.J. Kimber, M.J. Birket
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Stem Cell Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506123002489