Transient transfection of a wild-type p53 gene triggers resveratrol-induced apoptosis in cancer cells.

Resveratrol is a promising chemopreventive agent that mediates many cellular targets involved in cancer signaling pathways. p53 has been suggested to play a role in the anticancer properties of resveratrol. We investigated resveratrol-induced cytotoxicity in H1299 cells, which are non-small lung can...

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Bibliographic Details
Main Authors: Danielly Cristiny Ferraz da Costa, Fabiana Alves Casanova, Julia Quarti, Maitê Santos Malheiros, Daniel Sanches, Patricia Souza Dos Santos, Eliane Fialho, Jerson L Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3495968?pdf=render