Personalized monitoring of circulating tumor DNA with a specific signature of trackable mutations after chimeric antigen receptor T-cell therapy in follicular lymphoma patients

Personalized monitoring of circulating tumor DNA with a specific signature of trackable mutations after chimeric antigen receptor T-cell therapy in follicular lymphoma patients

BackgroundCART therapy has produced a paradigm shift in the treatment of relapsing FL patients. Strategies to optimize disease surveillance after these therapies are increasingly necessary. This study explores the potential value of ctDNA monitoring with an innovative signature of personalized track...

Full description

Bibliographic Details
Main Authors: Ana Jiménez-Ubieto, Alejandro Martín-Muñoz, María Poza, Sara Dorado, Almudena García-Ortiz, Enrique Revilla, Pilar Sarandeses, Yanira Ruiz-Heredia, Tycho Baumann, Antonia Rodríguez, María Calbacho, Pilar Martínez Sánchez, José María Sánchez Pina, Alejandro Martín García-Sancho, Gloria Figaredo, Daniel Gil-Alós, Laura Rufián, Margarita Rodríguez, Laura Carneros, Carolina Martínez-Laperche, Mariana Bastos-Oreiro, Chongwu Wang, María-Teresa Cedena, Inmaculada Rapado, Paula de Toledo, Miguel Gallardo, Antonio Valeri, Rosa Ayala, Joaquín Martínez-López, Santiago Barrio
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
follicular lymphoma
ctDNA (circulating tumor DNA)
NGS (Next-Generation Sequencing)
minimal residual disease
monitoring
PET/CT 18F-FDG
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1188818/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1188818/full

Similar Items