Stereospecificity of Ginsenoside AD-1 and AD-2 Showed Anticancer Activity via Inducing Mitochondrial Dysfunction and Reactive Oxygen Species Mediate Cell Apoptosis

Stereospecificity of Ginsenoside AD-1 and AD-2 Showed Anticancer Activity via Inducing Mitochondrial Dysfunction and Reactive Oxygen Species Mediate Cell Apoptosis

In this paper, the anti-cancer activity and molecular mechanisms of the isomers of AD-1 and AD-2 (20(<i>R</i>)-AD-1, 20(<i>R</i>)-AD-2, 20(<i>S</i>)-AD-1 and 20(<i>S</i>)-AD-2) were investigated. The results indicated that all of the four compounds obv...

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Bibliographic Details
Main Authors: Xude Wang, Meng Ding, Hong Zhao, Mengru Zhou, Xuan Lu, Yuanyuan Sun, Qinggao Zhang, Yuqing Zhao, Ruoyu Wang
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Molecules
Subjects:
AD-1 and AD-2
isomers
anti-cancer
apoptosis
ROS
Online Access:https://www.mdpi.com/1420-3049/28/18/6698

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https://www.mdpi.com/1420-3049/28/18/6698

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