Prognostic Impact of Caspase-8, CDK9 and Phospho-CDK9 (Thr 186) Expression in Patients with Uterine Cervical Cancer Treated with Definitive Chemoradiation and Brachytherapy

Prognostic Impact of Caspase-8, CDK9 and Phospho-CDK9 (Thr 186) Expression in Patients with Uterine Cervical Cancer Treated with Definitive Chemoradiation and Brachytherapy

<b>Introduction:</b> After primary platinum-based chemoradiation of locally advanced uterine cervical cancer, a substantial proportion of women present with persistent, recurrent or metastatic disease, indicating an unmet need for biomarker development. <b>Methods:</b> We eva...

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Bibliographic Details
Main Authors: Maximilian Fleischmann, Ranadip Mandal, Izabela Kostova, Monika Raab, Mourad Sanhaji, Stephanie Hehlgans, Markus Diefenhardt, Claus Rödel, Emmanouil Fokas, Klaus Strebhardt, Franz Rödel
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
caspase-8
CDK9
phospho-CDK9 (Thr 186)
prognosis
cervical cancer
radiochemotherapy
Online Access:https://www.mdpi.com/2072-6694/14/22/5500

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https://www.mdpi.com/2072-6694/14/22/5500

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