Early life exposure of infants to benzylpenicillin and gentamicin is associated with a persistent amplification of the gut resistome

Early life exposure of infants to benzylpenicillin and gentamicin is associated with a persistent amplification of the gut resistome

Abstract Background Infant gut microbiota is highly malleable, but the long-term longitudinal impact of antibiotic exposure in early life, together with the mode of delivery on infant gut microbiota and resistome, is not extensively studied. Methods Two hundred and eight samples from 45 infants coll...

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Bibliographic Details
Main Authors: Dhrati V. Patangia, Ghjuvan Grimaud, Carol-Anne O’Shea, C. A. Ryan, Eugene Dempsey, Catherine Stanton, R. Paul Ross
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Microbiome
Subjects:
Infant gut
Gut microbiota
Shotgun metagenomics
Resistome profile
Strain persistence
Online Access:https://doi.org/10.1186/s40168-023-01732-6

Internet

https://doi.org/10.1186/s40168-023-01732-6

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