Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma
Neuroblastoma (NB), although rare, accounts for 15% of all paediatric cancer mortality. Unusual among cancers, NBs lack a consistent set of gene mutations and, excluding large-scale chromosomal rearrangements, the genome seems to be largely intact. Indeed, many interesting features of NB suggest tha...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2015-05-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/8/5/429 |