Understanding Chemistry and Unique NMR Characters of Novel Amide and Ester Leflunomide Analogues

A series of diverse substituted 5-methyl-isoxazole-4-carboxylic acid amides, imide and esters in which the benzene ring is mono or disubstituted was prepared. Spectroscopic and conformational examination was investigated and a new insight involving steric interference and interesting downfield devia...

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Bibliographic Details
Main Authors: Morkos A. Henen, Abdelrahman Hamdi, Abdelbasset A. Farahat, Mohammed A. M. Massoud
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Magnetochemistry
Subjects:
Online Access:https://www.mdpi.com/2312-7481/3/4/41