Xanthoangelol modulates Caspase-1-dependent pyroptotic death among hepatocellular carcinoma cells with high expression of GSDMD

Xanthoangelol (XAG), a major chalcone presents in Angelica keiskei, has been employed in research to develop functional supplements or drugs due to its various pharmacological activities. Here, we investigated the underlying mechanism of XAG-induced cell death in hepatocellular carcinoma (HCC). We f...

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Bibliographic Details
Main Authors: Xuening Pang, Xiang Gao, Feng Liu, Yuhuan Jiang, Mingji Wang, Qun Li, Zichao Li
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464621002267