Use of mouse primary epidermal organoids for USA300 infection modeling and drug screening

Abstract Skin infections caused by drug-resistant Staphylococcus aureus occur at high rates nationwide. Mouse primary epidermal organoids (mPEOs) possess stratified histological and morphological characteristics of epidermis and are highly similar to their derived tissue at the transcriptomic and pr...

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Bibliographic Details
Main Authors: Xiaorui Xie, Xuebo Tong, Zhihong Li, Quan Cheng, Xiaowei Wang, Yin Long, Fangbo Liu, Yonghui Wang, Juan Wang, Li Liu
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05525-x