Calcitriol Prevents Neuroinflammation and Reduces Blood-Brain Barrier Disruption and Local Macrophage/Microglia Activation
Multiple sclerosis (MS) is a progressive disease of the central nervous system (CNS) that involves damage to the myelin sheath surrounding axons. MS therapy is based on immunomodulatory drugs that reduce disease recurrence and severity. Vitamin D is a hormone whose immunomodulatory ability has been...
Main Authors: | Larissa Ragozo Cardoso de Oliveira, Luiza Ayumi Nishiyama Mimura, Thais Fernanda de Campos Fraga-Silva, Larissa Lumi Watanabe Ishikawa, Ana Angélica Henrique Fernandes, Sofia Fernanda Gonçalves Zorzella-Pezavento, Alexandrina Sartori |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-03-01
|
Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fphar.2020.00161/full |
Similar Items
-
Experimental Autoimmune Encephalomyelitis Is Successfully Controlled by Epicutaneous Administration of MOG Plus Vitamin D Analog
by: Sofia Fernanda Gonçalves Zorzella-Pezavento, et al.
Published: (2017-10-01) -
Gliotoxin Aggravates Experimental Autoimmune Encephalomyelitis by Triggering Neuroinflammation
by: Thais Fernanda de Campos Fraga-Silva, et al.
Published: (2019-07-01) -
Organic Selenium Reaches the Central Nervous System and Downmodulates Local Inflammation: A Complementary Therapy for Multiple Sclerosis?
by: Juliana Helena dos Santos de Toledo, et al.
Published: (2020-10-01) -
Is there a window of opportunity for the therapeutic use of vitamin D in multiple sclerosis?
by: Sofia Fernanda Gonçalves Zorzella-Pezavento, et al.
Published: (2022-01-01) -
Systemic Infection by Non-<i>albicans Candida</i> Species Affects the Development of a Murine Model of Multiple Sclerosis
by: Thais Fernanda de Campos Fraga-Silva, et al.
Published: (2022-04-01)