Tetrahydrobiopterin Slows the Progression of Atherosclerosis

Tetrahydrobiopterin Slows the Progression of Atherosclerosis

We investigated whether oral tetrahydrobiopterin (BH4) treatment might slow the progression of atherosclerosis using hypercholesterolemic ApoE-knockout (KO) mice. We report that ingesting BH4 in drinking water is effective to inhibit atherogenesis in mice. Furthermore, we report that BH4 treatment i...

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Bibliographic Details
Main Authors: Kunihiro Suzuki, Hattori Yoshiyuki, Jojima Teruo, Tomizawa Atsuko, Okayasu Toshie, Kase Hiroyuki, Kawagoe Yoshiaki, Banba Nobuyuki, Monden Tsuyoshi, Nakanishi Nobuo, Kasai Kikuo
Format: Article
Language:English
Published: De Gruyter 2007-02-01
Series:Pteridines
Subjects:
tetrahydrobiopterin
apoe-ko mouse
atherosclerosis
endothelial function
Online Access:https://doi.org/10.1515/pteridines.2007.18.1.115

Internet

https://doi.org/10.1515/pteridines.2007.18.1.115

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