Accumulation of senescence observed in spinocerebellar ataxia type 7 mouse model.

Accumulation of senescence observed in spinocerebellar ataxia type 7 mouse model.

Spinocerebellar ataxia type 7 (SCA7) is a neurodegenerative disease caused by a trinucleotide CAG repeat. SCA7 predominantly causes a loss of photoreceptors in the retina and Purkinje cells of the cerebellum. Severe infantile-onset SCA7 also causes renal and cardiac irregularities. Previous reports...

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Bibliographic Details
Main Authors: William Miller, Charles Lewis Humphrey Pruett, William Stone, Cindy Eide, Megan Riddle, Courtney Popp, Matthew Yousefzadeh, Christopher Lees, Davis Seelig, Elizabeth Thompson, Harry Orr, Laura Niedernhofer, Jakub Tolar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0275580

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https://doi.org/10.1371/journal.pone.0275580

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