Engineering protein-based therapeutics through structural and chemical design

Abstract Protein-based therapeutics have led to new paradigms in disease treatment. Projected to be half of the top ten selling drugs in 2023, proteins have emerged as rivaling and, in some cases, superior alternatives to historically used small molecule-based medicines. This review chronicles both...

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Bibliographic Details
Main Authors: Sasha B. Ebrahimi, Devleena Samanta
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38039-x