Expression of Immuno-Oncologic Biomarkers Is Enriched in Colorectal Cancers and Other Solid Tumors Harboring the A59T Variant of <i>KRAS</i>

Expression of Immuno-Oncologic Biomarkers Is Enriched in Colorectal Cancers and Other Solid Tumors Harboring the A59T Variant of <i>KRAS</i>

The molecular heterogeneity of <i>KRAS</i> is well established, with a pool of variants comprising >75% of all known mutations; this pool includes mutations in classic codons 12, 13, and 61, as well as 146 and 117. In addition, there are rare variants that are more frequently encounte...

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Bibliographic Details
Main Authors: Emil Lou, Joanne Xiu, Yasmine Baca, Andrew C. Nelson, Benjamin A. Weinberg, Muhammad Shaalan Beg, Mohamed E. Salem, Heinz-Josef Lenz, Philip Philip, Wafik S. El-Deiry, W. Michael Korn
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cells
Subjects:
colon cancer
colorectal cancer
molecular oncology
oncogene
KRAS
A59T
Online Access:https://www.mdpi.com/2073-4409/10/6/1275

Internet

https://www.mdpi.com/2073-4409/10/6/1275

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