The genomics of disulfide bonding and protein stabilization in thermophiles.
Thermophilic organisms flourish in varied high-temperature environmental niches that are deadly to other organisms. Recently, genomic evidence has implicated a critical role for disulfide bonds in the structural stabilization of intracellular proteins from certain of these organisms, contrary to the...
Format: | Article |
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Language: | English |
Published: |
Public Library of Science (PLoS)
2005-09-01
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Series: | PLoS Biology |
Online Access: | http://dx.doi.org/10.1371/journal.pbio.0030309 |