The genomics of disulfide bonding and protein stabilization in thermophiles.

Thermophilic organisms flourish in varied high-temperature environmental niches that are deadly to other organisms. Recently, genomic evidence has implicated a critical role for disulfide bonds in the structural stabilization of intracellular proteins from certain of these organisms, contrary to the...

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Bibliographic Details
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-09-01
Series:PLoS Biology
Online Access:http://dx.doi.org/10.1371/journal.pbio.0030309