The mechanisms of intractable asthma
Overwhelming evidence now points to asthma as a chronic inflammatory disease involving the airways. The T lymphocyte takes primacy in driving the inflammatory response through upregulation of cytokines, specifically those encoded in the IL-4 gene cluster: IL-4 and IL-13 (IgE isotype switching); IL-3...
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Format: | Article |
Language: | English |
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Elsevier
1996-01-01
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Series: | Allergology International |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S1323893015316142 |