The mechanisms of intractable asthma

Overwhelming evidence now points to asthma as a chronic inflammatory disease involving the airways. The T lymphocyte takes primacy in driving the inflammatory response through upregulation of cytokines, specifically those encoded in the IL-4 gene cluster: IL-4 and IL-13 (IgE isotype switching); IL-3...

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Bibliographic Details
Main Author: Stephen T Holgate
Format: Article
Language:English
Published: Elsevier 1996-01-01
Series:Allergology International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015316142