Survivin S81A Enhanced TRAIL's Activity in Inducing Apoptosis

BACKGROUND: Survivin is rarely expressed in normal healthy adult tissues, however, it is upregulated in the majority of cancers. Survivin, which belongs to IAPs family, has been widely reported to protect cells from apoptosis by inhibiting caspases pathway. Survivin’s mitotic activity is modulated b...

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Bibliographic Details
Main Authors: Ferry Sandra, Roya Khosravi-Far
Format: Article
Language:English
Published: Secretariat of The Indonesian Biomedical Journal 2010-12-01
Series:Indonesian Biomedical Journal
Online Access:http://inabj.org/index.php/ibj/article/view/124