Longitudinal study of leukocyte DNA methylation and biomarkers for cancer risk in older adults

Longitudinal study of leukocyte DNA methylation and biomarkers for cancer risk in older adults

Abstract Background Changes in DNA methylation over the course of life may provide an indicator of risk for cancer. We explored longitudinal changes in CpG methylation from blood leukocytes, and likelihood of future cancer diagnosis. Methods Peripheral blood samples were obtained at baseline and at...

Full description

Bibliographic Details
Main Authors: Alexandra H. Bartlett, Jane W. Liang, Jose Vladimir Sandoval-Sierra, Jay H. Fowke, Eleanor M. Simonsick, Karen C. Johnson, Khyobeni Mozhui
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Biomarker Research
Subjects:
Cancer
DNA methylation
Biomarker
Epigenetics
Online Access:http://link.springer.com/article/10.1186/s40364-019-0161-3

Internet

http://link.springer.com/article/10.1186/s40364-019-0161-3

Similar Items