Tumor infiltrating lymphocyte stratification of prognostic staging of early-stage triple negative breast cancer

Abstract The importance of integrating biomarkers into the TNM staging has been emphasized in the 8th Edition of the American Joint Committee on Cancer (AJCC) Staging system. In a pooled analysis of 2148 TNBC-patients in the adjuvant setting, TILs are found to strongly up and downstage traditional p...

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Main Authors: Sherene Loi, Roberto Salgado, Sylvia Adams, Giancarlo Pruneri, Prudence A. Francis, Magali Lacroix-Triki, Heikki Joensuu, Maria Vittoria Dieci, Sunil Badve, Sandra Demaria, Robert Gray, Elisabetta Munzone, Damien Drubay, Jerome Lemonnier, Christos Sotiriou, Pirkko Liisa Kellokumpu-Lehtinen, Andrea Vingiani, Kathryn Gray, Fabrice André, Carsten Denkert, Martine Piccart, Elvire Roblin, Stefan Michiels
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-021-00362-1