Endometrial mesenchymal stem cells isolated from menstrual blood repaired epirubicin-induced damage to human ovarian granulosa cells by inhibiting the expression of Gadd45b in cell cycle pathway

Endometrial mesenchymal stem cells isolated from menstrual blood repaired epirubicin-induced damage to human ovarian granulosa cells by inhibiting the expression of Gadd45b in cell cycle pathway

Abstract Background To explore the effect of mesenchymal stem cells isolated from menstrual blood (MB-MSCs) on epirubicin-induced damage to human ovarian granulosa cells (GCs) and its potential mechanisms. Methods The estradiol, progesterone, anti-Müllerian hormone, inhibin A, and inhibin B levels w...

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Bibliographic Details
Main Authors: Zhongrui Yan, Fengyi Guo, Qing Yuan, Yu Shao, Yedan Zhang, Huiyan Wang, Shaohua Hao, Xue Du
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Stem Cell Research & Therapy
Subjects:
Menstrual blood
Mesenchymal stem cells
Granulosa cells
Premature ovarian failure
Epirubicin
Gadd45b
Online Access:http://link.springer.com/article/10.1186/s13287-018-1101-0

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http://link.springer.com/article/10.1186/s13287-018-1101-0

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