A Novel Single-Step-Labeled <sup>212</sup>Pb-CaCO<sub>3</sub> Microparticle for Internal Alpha Therapy: Preparation, Stability, and Preclinical Data from Mice

A Novel Single-Step-Labeled <sup>212</sup>Pb-CaCO<sub>3</sub> Microparticle for Internal Alpha Therapy: Preparation, Stability, and Preclinical Data from Mice

Lead-212 is recognized as a promising radionuclide for targeted alpha therapy for tumors. Many studies of <sup>212</sup>Pb-labeling of various biomolecules through bifunctional chelators have been conducted. Another approach to exploiting the cytotoxic effect is coupling the radionuclide...

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Bibliographic Details
Main Authors: Ruth Gong Li, Kim Lindland, Tina Bjørnlund Bønsdorff, Sara Westrøm, Roy Hartvig Larsen
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Materials
Subjects:
lead-212
alpha therapy
radionuclide therapy
radiopharmaceutical
calcium carbonate
microparticles
Online Access:https://www.mdpi.com/1996-1944/14/23/7130

Internet

https://www.mdpi.com/1996-1944/14/23/7130

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