Binding affinity between coronavirus spike protein and human ACE2 receptor

Binding affinity between coronavirus spike protein and human ACE2 receptor

Coronaviruses (CoVs) pose a major risk to global public health due to their ability to infect diverse animal species and potential for emergence in humans. The CoV spike protein mediates viral entry into the cell and plays a crucial role in determining the binding affinity to host cell receptors. Wi...

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Bibliographic Details
Main Authors: Marcus Ho-Hin Shum, Yang Lee, Leighton Tam, Hui Xia, Oscar Lung-Wa Chung, Zhihong Guo, Tommy Tsan-Yuk Lam
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Coronavirus
Spike protein
Binding affinity
Receptor use
Human ACE2
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037024000102

Internet

http://www.sciencedirect.com/science/article/pii/S2001037024000102

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