Systemic Deficiency of PTEN Accelerates Breast Cancer Growth and Metastasis

Systemic Deficiency of PTEN Accelerates Breast Cancer Growth and Metastasis

Mutation or loss of the tumor suppressor gene PTEN or its functional status in tumor stromal cells may affect tumor occurrence, development, invasion, and metastasis, in which, however, the role of overall low PTEN expression, mutation, or deletion in the tumor-bearing host has rarely been reported....

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Bibliographic Details
Main Authors: Jing Chen, Jingjing Sun, Qunfeng Wang, Yanze Du, Jie Cheng, Juan Yi, Bei Xie, Suya Jin, Gang Chen, Lina Wang, Xiaoyuan Wang, Hulai Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Oncology
Subjects:
PTEN
4T1 cell
multiplication
invasion
metastasis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.825484/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.825484/full

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