Loss of CD28 on Peripheral T Cells Decreases the Risk for Early Acute Rejection after Kidney Transplantation.

End-stage renal disease patients have a dysfunctional, prematurely aged peripheral T-cell system. Here we hypothesized that the degree of premature T-cell ageing before kidney transplantation predicts the risk for early acute allograft rejection (EAR).222 living donor kidney transplant recipients we...

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Bibliographic Details
Main Authors: Burç Dedeoglu, Ruud W J Meijers, Mariska Klepper, Dennis A Hesselink, Carla C Baan, Nicolle H R Litjens, Michiel G H Betjes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4780739?pdf=render